Formaldehyde Adduct Formation in Peptides From Rubber Stoppers
Learn how trace formaldehyde leached from rubber stoppers and elastomeric closures forms Schiff base adducts with peptide amino acids during storage in vials.
Tag: rubber stopper leachables
Peptide Cysteine Thiol Alkylation From Rubber Stopper Leachables
Learn how peptide cysteine thiol alkylation occurs when electrophilic leachables from butyl rubber stoppers and residual reagents react with free thiol groups during storage.
Rubber Stopper Leachables in Peptide Storage Solutions
How rubber stopper leachables and extractables contaminate reconstituted peptide solutions during storage, causing oxidative degradation and particulate formation.