Peptide Aspartate Isomerization During Refrigerated Storage
Learn how reconstituted peptides undergo aspartate isomerization via succinimide formation at Asp-Gly, Asp-Ser, and Asp-Thr motifs in acidic storage solutions.
Tag: isoaspartate accumulation
Aspartate Isomerization in Stored Peptides: Succinimide Risk
Learn how aspartate isomerization and isoaspartate accumulation via succinimide intermediates degrade reconstituted peptides at Asp-Gly, Asp-Ser, and Asp-Thr motifs during storage.
Peptide Aspartate Isomerization: Isoaspartate Storage Risk
Learn how peptide aspartate isomerization through succinimide ring closure at Asp-Gly and Asp-Ser motifs generates isoaspartate residues that degrade potency during storage.