Asp-Pro Peptide Bond Cleavage During Storage Explained
Learn how Asp-Pro peptide bond cleavage occurs during extended storage through acid-catalyzed hydrolysis, cyclic anhydride intermediates, and why proline is uniquely susceptible.
Tag: acid-catalyzed hydrolysis
Asp-Pro Peptide Bond Cleavage in Reconstituted Peptides
Learn how Asp-Pro peptide bond cleavage occurs during storage via acid-catalyzed hydrolysis, cyclic anhydride intermediates, and prolyl nitrogen protonation.